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Paeoniflorin mitigates high glucose-induced lifespan reduction by inhibiting insulin signaling in Caenorhabditis elegans

In organisms, high glucose can cause several aspects of toxicity, including the lifespan reduction. Paeoniflorin is the major component of Paeoniaceae plants. Nevertheless, the possible effect of paeoniflorin to suppress high glucose toxicity in reducing lifespan and underlying mechanism are largely...

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Detalles Bibliográficos
Autores principales: Liu, Tianwen, Zhuang, Ziheng, Wang, Dayong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10315627/
https://www.ncbi.nlm.nih.gov/pubmed/37405055
http://dx.doi.org/10.3389/fphar.2023.1202379