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Aberrant expression of NPPB through YAP1 and TAZ activation in mesothelioma with Hippo pathway gene alterations

BACKGROUND: Mesothelioma is a neoplastic disease associated with asbestos exposure. It is highly malignant and has a poor prognosis; thus, early detection is desirable. Recent whole‐genome analysis has revealed that mesothelioma is characterized by a high frequency of mutations in a set of genes inv...

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Detalles Bibliográficos
Autores principales: Sato, Tatsuhiro, Akao, Ken, Sato, Ayuko, Tsujimura, Tohru, Mukai, Satomi, Sekido, Yoshitaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10315720/
https://www.ncbi.nlm.nih.gov/pubmed/37165917
http://dx.doi.org/10.1002/cam4.6056