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Time‐dependent effects of hypoxia on cell metabolism, signaling, and iron homeostasis in the hematopoietic progenitor model KG1a

Lowered availability of oxygen in the micro‐environment of cells perturbs metabolic and signaling pathways. It affects proliferation, tissue morphology, and differentiation. Leukemia impairs maturation of hematopoietic progenitors: the immune system, healing, and erythropoiesis are weakened, thereby...

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Detalles Bibliográficos
Autores principales: Nahoui‐Zarouri, Inès, Léger, Claire, El Samra, Ghina, Cottet‐Rousselle, Cécile, Moulis, Jean‐Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10315738/
https://www.ncbi.nlm.nih.gov/pubmed/36416440
http://dx.doi.org/10.1002/2211-5463.13527