Induction of endoplasmic reticulum stress is associated with the anti‐tumor activity of monepantel across cancer types

BACKGROUND: Monepantel is an anti‐helminthic drug that also has anti‐cancer properties. Despite several studies over the years, the molecular target of monepantel in mammalian cells is still unknown, and its mechanism‐of‐action is not fully understood, though effects on cell cycle, mTOR signalling a...

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Detalles Bibliográficos
Autores principales: Harris, Tiffany J., Liao, Yang, Shi, Wei, Evangelista, Marco, Pal, Bhupinder, Puthalakath, Hamsa, Aston, Roger, Mollard, Richard, Mariadason, John M., Lee, Erinna F., Fairlie, Walter D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
RESEARCH ARTICLES
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10315739/
https://www.ncbi.nlm.nih.gov/pubmed/37148543
http://dx.doi.org/10.1002/cam4.6021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10315739/
https://www.ncbi.nlm.nih.gov/pubmed/37148543
http://dx.doi.org/10.1002/cam4.6021

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