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Induction of endoplasmic reticulum stress is associated with the anti‐tumor activity of monepantel across cancer types
BACKGROUND: Monepantel is an anti‐helminthic drug that also has anti‐cancer properties. Despite several studies over the years, the molecular target of monepantel in mammalian cells is still unknown, and its mechanism‐of‐action is not fully understood, though effects on cell cycle, mTOR signalling a...
Autores principales: | Harris, Tiffany J., Liao, Yang, Shi, Wei, Evangelista, Marco, Pal, Bhupinder, Puthalakath, Hamsa, Aston, Roger, Mollard, Richard, Mariadason, John M., Lee, Erinna F., Fairlie, Walter D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10315739/ https://www.ncbi.nlm.nih.gov/pubmed/37148543 http://dx.doi.org/10.1002/cam4.6021 |
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