Analysis of thymic generation of shared T‐cell receptor α repertoire associated with recognition of tumor antigens shows no preference for neoantigens over wild‐type antigens

BACKGROUND: The number of mutations in cancer cells is an important predictor of a positive response to cancer immunotherapy. It has been suggested that the neoantigens produced by these mutations are more immunogenic than nonmutated tumor antigens, which are likely to be protected by immunological...

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Detalles Bibliográficos
Autores principales: Mattila, Joonatan, Sormunen, Silja, Heikkilä, Nelli, Mattila, Ilkka P., Saramäki, Jari, Arstila, T. Petteri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
RESEARCH ARTICLES
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10315763/
https://www.ncbi.nlm.nih.gov/pubmed/37114587
http://dx.doi.org/10.1002/cam4.6002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10315763/
https://www.ncbi.nlm.nih.gov/pubmed/37114587
http://dx.doi.org/10.1002/cam4.6002

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