LAG‐3 transcriptomic expression patterns across malignancies: Implications for precision immunotherapeutics

BACKGROUND: Lymphocyte activation gene 3 (LAG‐3) or CD223 is a transmembrane protein that serves as an immune checkpoint which attenuates T‐cell activation. Many clinical trials of LAG‐3 inhibitors have had modest effects, but recent data indicate that the LAG‐3 antibody relatlimab, together with ni...

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Detalles Bibliográficos
Autores principales: Adashek, Jacob J., Kato, Shumei, Nishizaki, Daisuke, Miyashita, Hirotaka, De, Pradip, Lee, Suzanna, Pabla, Sarabjot, Nesline, Mary, Conroy, Jeffrey M., DePietro, Paul, Lippman, Scott, Kurzrock, Razelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
RESEARCH ARTICLES
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10315766/
https://www.ncbi.nlm.nih.gov/pubmed/37132280
http://dx.doi.org/10.1002/cam4.6000

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10315766/
https://www.ncbi.nlm.nih.gov/pubmed/37132280
http://dx.doi.org/10.1002/cam4.6000

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