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Birth of a poly(A) tail: mechanisms and control of mRNA polyadenylation

During their synthesis in the cell nucleus, most eukaryotic mRNAs undergo a two‐step 3′‐end processing reaction in which the pre‐mRNA is cleaved and released from the transcribing RNA polymerase II and a polyadenosine (poly(A)) tail is added to the newly formed 3′‐end. These biochemical reactions mi...

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Detalles Bibliográficos
Autores principales: Rodríguez‐Molina, Juan B., Turtola, Matti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10315857/
https://www.ncbi.nlm.nih.gov/pubmed/36416579
http://dx.doi.org/10.1002/2211-5463.13528