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Synthesis of tetrahydrofuro[3,2-c]pyridines via Pictet–Spengler reaction
A semi-one-pot method for the synthesis of 4-substituted tetrahydrofuro[3,2-c]pyridines by the Pictet–Spengler reaction was developed. The method is based on the condensation of easily accessibly 2-(5-methylfuran-2-yl)ethanamine with commercially available aromatic aldehydes followed by acid-catalyz...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Beilstein-Institut
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10315887/ https://www.ncbi.nlm.nih.gov/pubmed/37404803 http://dx.doi.org/10.3762/bjoc.19.74 |