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Synthesis of tetrahydrofuro[3,2-c]pyridines via Pictet–Spengler reaction

A semi-one-pot method for the synthesis of 4-substituted tetrahydrofuro[3,2-c]pyridines by the Pictet–Spengler reaction was developed. The method is based on the condensation of easily accessibly 2-(5-methylfuran-2-yl)ethanamine with commercially available aromatic aldehydes followed by acid-catalyz...

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Detalles Bibliográficos
Autores principales:	Mendogralo, Elena Y, Uchuskin, Maxim G
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Beilstein-Institut 2023
Materias:	Full Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10315887/ https://www.ncbi.nlm.nih.gov/pubmed/37404803 http://dx.doi.org/10.3762/bjoc.19.74

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