piCRISPR: Physically informed deep learning models for CRISPR/Cas9 off-target cleavage prediction

CRISPR/Cas programmable nuclease systems have become ubiquitous in the field of gene editing. With progressing development, applications in in vivo therapeutic gene editing are increasingly within reach, yet limited by possible adverse side effects from unwanted edits. Recent years have thus seen co...

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Detalles Bibliográficos
Autores principales: Störtz, Florian, Mak, Jeffrey K., Minary, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10316064/
https://www.ncbi.nlm.nih.gov/pubmed/38047242
http://dx.doi.org/10.1016/j.ailsci.2023.100075

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10316064/
https://www.ncbi.nlm.nih.gov/pubmed/38047242
http://dx.doi.org/10.1016/j.ailsci.2023.100075

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