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piCRISPR: Physically informed deep learning models for CRISPR/Cas9 off-target cleavage prediction
CRISPR/Cas programmable nuclease systems have become ubiquitous in the field of gene editing. With progressing development, applications in in vivo therapeutic gene editing are increasingly within reach, yet limited by possible adverse side effects from unwanted edits. Recent years have thus seen co...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier B.V
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10316064/ https://www.ncbi.nlm.nih.gov/pubmed/38047242 http://dx.doi.org/10.1016/j.ailsci.2023.100075 |