P53/MDM2 Complex-Based Targeted Strategies in Colon Adenocarcinoma

In the current molecular review, we describe the mechanisms of TP53/MDM2 deregulation and their impact on the colon adenocarcinoma molecular substrate and phenotype. Among the genes that are critically altered in carcinogenesis, the TP53 tumor suppressor gene is of major importance. The TP53 gene (g...

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Detalles Bibliográficos
Autores principales: Niotis, Athanasios, Tsiambas, Evangelos, Dimitroulis, Dimitrios, Sarlanis, Helen, Falidas, Evangelos, Kavantzas, Nikolaos, Constantinides, Constantinos A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academy of Sciences and Arts of Bosnia and Herzegovina 2023
Materias:
Narrative Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10316079/
https://www.ncbi.nlm.nih.gov/pubmed/37326394
http://dx.doi.org/10.5644/ama2006-124.398

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10316079/
https://www.ncbi.nlm.nih.gov/pubmed/37326394
http://dx.doi.org/10.5644/ama2006-124.398

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