Cargando…

P53/MDM2 Complex-Based Targeted Strategies in Colon Adenocarcinoma

In the current molecular review, we describe the mechanisms of TP53/MDM2 deregulation and their impact on the colon adenocarcinoma molecular substrate and phenotype. Among the genes that are critically altered in carcinogenesis, the TP53 tumor suppressor gene is of major importance. The TP53 gene (g...

Descripción completa

Detalles Bibliográficos
Autores principales:	Niotis, Athanasios, Tsiambas, Evangelos, Dimitroulis, Dimitrios, Sarlanis, Helen, Falidas, Evangelos, Kavantzas, Nikolaos, Constantinides, Constantinos A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Academy of Sciences and Arts of Bosnia and Herzegovina 2023
Materias:	Narrative Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10316079/ https://www.ncbi.nlm.nih.gov/pubmed/37326394 http://dx.doi.org/10.5644/ama2006-124.398

Ejemplares similares

Impact of Immune-Inflammatory Microenvironment Alterations on the Bronchial Lumen of Children With Protracted Bacterial Bronchitis
por: Ntesou, Despoina, et al.
Publicado: (2021)

Caspase 8 Expression Patterns in Meningiomas: A Tissue Microarray Digital Image Analysis
por: Roukas, Dimitrios, et al.
Publicado: (2022)

Persistent Coughing as the First Symptom of Primary Mucinous Appendiceal Adenocarcinoma
por: Gourgiotis, Stavros, et al.
Publicado: (2015)

The Goodness-of-fit of the Fractal Dimension as a Diagnostic Factor in Breast Cancer
por: Maipas, Sotirios, et al.
Publicado: (2018)

Impact of Ribosome Activity on SARS-CoV-2 LNP – Based mRNA Vaccines
por: Tsiambas, Evangelos, et al.
Publicado: (2021)

Researching the Phenomenon of Poor Ovarian Responders and Management Strategies in IVF: A Narrative Review
por: Galatis, Dionysios, et al.
Publicado: (2022)

Recurrent Urinary Tract Infections due to Asymptomatic Colonic Diverticulitis
por: Falidas, Evangelos, et al.
Publicado: (2012)

Coronavirus in Hematologic Malignancies: Targeting Molecules Beyond the Angiotensin-Converting Enzyme 2 (ACE2) Wall in COVID-19
por: Tsiambas, Evangelos, et al.
Publicado: (2020)

A type of neoplasia deadlier than gastric adenocarcinoma? Report of a case of primary gastric squamous cell carcinoma
por: Vailas, Michail G., et al.
Publicado: (2019)

Dance/Movement Therapy and the Arts in Healthcare: The First 50 Years
por: Goodill, Sherry W.
Publicado: (2016)

Perspective from a Patient Partner
por: Gaetz, Lyn
Publicado: (2020)

How COVID-19 Is Testing and Evolving Our Communication Skills
por: Julka-Anderson, Naman
Publicado: (2020)

Learning to Work Together—a BRIDGE to Engagement
por: Houlihan, Mary Ellen
Publicado: (2021)

An End-User’s Personal Perspective on the Need of Consumer Involvement in Research
por: Ferry, S. M., et al.
Publicado: (2022)

“Not all groups come together, but this one just clicks”: Ten Tips for Sustaining an Engagement Panel
por: Jensen, Agnes C., et al.
Publicado: (2022)

A Sample of the Future: Digital Health and Near-Patient Testing
por: Grys, Thomas E., et al.
Publicado: (2023)

Lactose digestion in humans: intestinal lactase appears to be constitutive whereas the colonic microbiome is adaptable
por: Forsgård, Richard A
Publicado: (2019)

Cognitive debiasing 2: impediments to and strategies for change
por: Croskerry, Pat, et al.
Publicado: (2013)

The patient is in: patient involvement strategies for diagnostic error mitigation
por: McDonald, Kathryn M, et al.
Publicado: (2013)

Same Chance of Accessing Resection? Impact of Socioeconomic Status on Resection Rates Among Patients with Pancreatic Adenocarcinoma—A Systematic Review
por: Thobie, Alexandre, et al.
Publicado: (2021)

Designing an ARDS trial for 2020 and beyond: focus on enrichment strategies
por: Ware, Lorraine B., et al.
Publicado: (2020)

Sleep Assessment in Critically Ill Adults: Established Methods and Emerging Strategies
por: Weinhouse, Gerald L., et al.
Publicado: (2022)

Diagnostic strategies for SARS-CoV-2 infection and interpretation of microbiological results
por: Caruana, G., et al.
Publicado: (2020)

Clinical strategies for implementing lung and diaphragm-protective ventilation: avoiding insufficient and excessive effort
por: Goligher, Ewan C., et al.
Publicado: (2020)

Evolution of prostate MRI: from multiparametric standard to less-is-better and different-is better strategies
por: Girometti, Rossano, et al.
Publicado: (2019)

Molecular Mechanisms of New Bone Formation in Axial Spondyloarthritis
por: Klavdianou, Kalliopi, et al.
Publicado: (2022)

Multiple giant diverticula of the jejunum causing intestinal obstruction: report of a case and review of the literature
por: Falidas, Evangelos, et al.
Publicado: (2011)

Sigmoid carcinoma localized in the sac of a right inguinoscrotal hernia
por: Falidas, Evangelos, et al.
Publicado: (2015)

Strategies to Optimize ICU Liberation (A to F) Bundle Performance in Critically Ill Adults With Coronavirus Disease 2019
por: Devlin, John W., et al.
Publicado: (2020)

Chromosome X riddle in SARS-CoV-2 (COVID-19) - related lung pathology
por: Tsiambas, Evangelos, et al.
Publicado: (2020)

Ephrin (Eph) receptor A1, A4, A5 and A7 expression in human non-small cell lung carcinoma: associations with clinicopathological parameters, tumor proliferative capacity and patients’ survival
por: Giaginis, Constantinos, et al.
Publicado: (2014)

Reducing unnecessary urinary catheter use and other strategies to prevent catheter-associated urinary tract infection: an integrative review
por: Meddings, Jennifer, et al.
Publicado: (2014)

Anatomical Variations of Vascular Anatomy in Meckel’s Diverticulum
por: Ntalianis, Dimitrios Malligiannis, et al.
Publicado: (2022)

Artificial Macrocycles as Potent p53–MDM2 Inhibitors
por: Estrada-Ortiz, Natalia, et al.
Publicado: (2017)

Telling the story of complex change: an Impact Framework for the real world
por: Willett, Jo, et al.
Publicado: (2021)

Complexities of deep learning-based undersampled MR image reconstruction
por: Noordman, Constant Richard, et al.
Publicado: (2023)

Sclerosing Mesenteritis: Diverse clinical presentations and dissimilar treatment options. A case series and review of the literature
por: Vlachos, Konstantinos, et al.
Publicado: (2011)

Pneumoperitoneum, Retropneumoperitoneum, Pneumomediastinum, and Diffuse Subcutaneous Emphysema following Diagnostic Colonoscopy
por: Falidas, Evangelos, et al.
Publicado: (2012)

Multicystic Hepatocarcinoma Mimicking Liver Abscess
por: Falidas, Evangelos, et al.
Publicado: (2013)

Rectus Abdominis Muscle Malignant Fibrous Histiocytoma Causing a Large Abdominal Wall Defect: Reconstruction with Biological Mesh
por: Falidas, Evangelos, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_0s9g4ffeengdfkeb0r5kgshr9v