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Thermotoga maritima oriC involves a DNA unwinding element with distinct modules and a DnaA-oligomerizing region with a novel directional binding mode

Initiation of chromosomal replication requires dynamic nucleoprotein complexes. In most eubacteria, the origin oriC contains multiple DnaA box sequences to which the ubiquitous DnaA initiators bind. In Escherichia coli oriC, DnaA boxes sustain construction of higher-order complexes via DnaA–DnaA int...

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Detalles Bibliográficos
Autores principales: Lu, Chuyuan, Yoshida, Ryusei, Katayama, Tsutomu, Ozaki, Shogo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10316083/
https://www.ncbi.nlm.nih.gov/pubmed/37276959
http://dx.doi.org/10.1016/j.jbc.2023.104888