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Hydrogen sulfide ameliorates abdominal aorta coarctation-induced myocardial fibrosis by inhibiting pyroptosis through regulating eukaryotic translation initiation factor 2α phosphorylation and activating PI3K/AKT1 pathway

This study aimed to assess the effects of exogenous hydrogen sulfide (H(2)S) on abdominal aorta coarctation (AAC) induced myocardial fibrosis (MF) and autophagy in rats. Forty-four Sprague–Dawley rats were randomly divided into control group, AAC group, AAC + H(2)S group, and H(2)S control group. Af...

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Detalles Bibliográficos
Autores principales: Li, Yaling, Wu, Zhixiong, Hu, Jiangping, Liu, Gongli, Hu, Hongming, Ouyang, Fan, Yang, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Physiological Society and The Korean Society of Pharmacology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10316187/
https://www.ncbi.nlm.nih.gov/pubmed/37386832
http://dx.doi.org/10.4196/kjpp.2023.27.4.345