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Encainide, a class Ic anti-arrhythmic agent, blocks voltage-dependent potassium channels in coronary artery smooth muscle cells

Voltage-dependent K(+) (Kv) channels are widely expressed on vascular smooth muscle cells and regulate vascular tone. Here, we explored the inhibitory effect of encainide, a class Ic anti-arrhythmic agent, on Kv channels of vascular smooth muscle from rabbit coronary arteries. Encainide inhibited Kv...

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Detalles Bibliográficos
Autores principales: Li, Hongliang, Zhou, Yue, Yang, Yongqi, Zha, Yiwen, Ye, Bingqian, Mun, Seo-Yeong, Zhuang, Wenwen, Liang, Jingyan, Park, Won Sun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Physiological Society and The Korean Society of Pharmacology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10316191/
https://www.ncbi.nlm.nih.gov/pubmed/37386837
http://dx.doi.org/10.4196/kjpp.2023.27.4.399