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Dihydroaustrasulfone alcohol induces apoptosis in nasopharyngeal cancer cells by inducing reactive oxygen species-dependent inactivation of the PI3K/AKT pathway

Dihydroaustrasulfone alcohol (DA), the synthetic precursor of a natural compound (austrasulfone) isolated from the coral species Cladiella australis, has shown cytotoxic effects against cancer cells. However, it is unknown whether DA has antitumor effects on nasopharyngeal carcinoma (NPC). In this s...

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Detalles Bibliográficos
Autores principales: Tan, Kok-Tong, Shih, Yu-Hung, Gong, Jiny Yin, Zhang, Xiang, Huang, Chiung-Yao, Su, Jui-Hsin, Sheu, Jyh-Horng, Lin, Chi-Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Physiological Society and The Korean Society of Pharmacology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10316192/
https://www.ncbi.nlm.nih.gov/pubmed/37386836
http://dx.doi.org/10.4196/kjpp.2023.27.4.383