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Shikonin ameliorates salivary gland damage and inflammation in a mouse model of Sjögren’s syndrome by modulating MAPK signaling pathway

Sjögren syndrome (SS) is a systemic inflammatory autoimmune disease that involves exocrine glands. Shikonin is extracted from comfrey, which is conventionally used as an anti-tumor, antibacterial, and antiviral drug in China. However, the application of Shikonin in SS remains unreported. This study...

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Detalles Bibliográficos
Autores principales: Guo, Wenjing, Wang, Xin, Sun, Chao, Wang, Jian, Wang, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Physiological Society and The Korean Society of Pharmacology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10316193/
https://www.ncbi.nlm.nih.gov/pubmed/37386833
http://dx.doi.org/10.4196/kjpp.2023.27.4.357