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Adipocytes control hematopoiesis and inflammation through CD40 signaling

The co-stimulatory CD40-CD40L dyad plays an important role in chronic inflammatory diseases associated with aging. Although CD40 is mainly expressed by immune cells, CD40 is also present on adipocytes. We aimed to delineate the role of adipocyte CD40 in the aging hematopoietic system and evaluated t...

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Detalles Bibliográficos
Autores principales: Reiche, Myrthe E., Poels, Kikkie, Bosmans, Laura A., Vos, Winnie G., van Tiel, Claudia M., Gijbels, Marion J.J., Aarts, Suzanne A.B.M., den Toom, Myrthe, Beckers, Linda, Weber, Christian, Atzler, Dorothee, Rensen, Patrick C.N., Kooijman, Sander, Lutgens, Esther
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Fondazione Ferrata Storti 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10316249/
https://www.ncbi.nlm.nih.gov/pubmed/36475519
http://dx.doi.org/10.3324/haematol.2022.281482