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Adipocytes control hematopoiesis and inflammation through CD40 signaling
The co-stimulatory CD40-CD40L dyad plays an important role in chronic inflammatory diseases associated with aging. Although CD40 is mainly expressed by immune cells, CD40 is also present on adipocytes. We aimed to delineate the role of adipocyte CD40 in the aging hematopoietic system and evaluated t...
Autores principales: | Reiche, Myrthe E., Poels, Kikkie, Bosmans, Laura A., Vos, Winnie G., van Tiel, Claudia M., Gijbels, Marion J.J., Aarts, Suzanne A.B.M., den Toom, Myrthe, Beckers, Linda, Weber, Christian, Atzler, Dorothee, Rensen, Patrick C.N., Kooijman, Sander, Lutgens, Esther |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Fondazione Ferrata Storti
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10316249/ https://www.ncbi.nlm.nih.gov/pubmed/36475519 http://dx.doi.org/10.3324/haematol.2022.281482 |
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