Transcriptome analysis in acute gastrointestinal graft-versus host disease reveals a unique signature in children and shared biology with pediatric inflammatory bowel disease

We performed transcriptomic analyses on freshly frozen (n=21) and paraffin-embedded (n=35) gastrointestinal (GI) biopsies from children with and without acute acute GI graft-versus-host disease (GvHD) to study differential gene expressions. We identified 164 significant genes, 141 upregulated and 23...

Descripción completa

Detalles Bibliográficos
Autores principales: Khandelwal, Pooja, Lounder, Dana T., Bartlett, Allison, Haberman, Yael, Jegga, Anil G., Ghandikota, Sudhir, Koo, Jane, Luebbering, Nathan, Leino, Daniel, Abdullah, Sheyar, Loveless, Michaela, Minar, Phillip, Lake, Kelly, Litts, Bridget, Karns, Rebekah, Nelson, Adam S., Denson, Lee A., Davies, Stella M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Fondazione Ferrata Storti 2023
Materias:
Article - Bone Marrow Transplantation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10316272/
https://www.ncbi.nlm.nih.gov/pubmed/36727399
http://dx.doi.org/10.3324/haematol.2022.282035

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10316272/
https://www.ncbi.nlm.nih.gov/pubmed/36727399
http://dx.doi.org/10.3324/haematol.2022.282035

Ejemplares similares