Plasminogen activator-coated nanobubbles targeting cell-bound β2-glycoprotein I as a novel thrombus-specific thrombolytic strategy

β2-glycoprotein I (β2-GPI) is a serum protein widely recognized as the main target of antibodies present in patients with antiphospholipid syndrome (APS). β2-GPI binds to activated endothelial cells, platelets and leukocytes, key players in thrombus formation. We developed a new targeted thrombolyti...

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Detalles Bibliográficos
Autores principales: Macor, Paolo, Durigutto, Paolo, Argenziano, Monica, Smith-Jackson, Kate, Capolla, Sara, Di Leonardo, Valeria, Marchbank, Kevin, Tolva, Valerio Stefano, Semeraro, Fabrizio, Ammollo, Concetta T., Colucci, Mario, Cavalli, Roberta, Meroni, Pierluigi, Tedesco, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Fondazione Ferrata Storti 2022
Materias:
Article - Coagulation & its Disorders
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10316273/
https://www.ncbi.nlm.nih.gov/pubmed/36172817
http://dx.doi.org/10.3324/haematol.2022.281505

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10316273/
https://www.ncbi.nlm.nih.gov/pubmed/36172817
http://dx.doi.org/10.3324/haematol.2022.281505

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