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Histone Modification of Osteogenesis Related Genes Triggered by Substrate Topography Promotes Human Mesenchymal Stem Cell Differentiation

[Image: see text] The clinical success of orthopedic implants is closely related to their integration in the bone tissue promoted by rough device surfaces. The biological response of precursor cells to their artificial microenvironments plays a critical role in this process. In this study, we elucid...

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Detalles Bibliográficos
Autores principales: Xu, Xun, Wang, Weiwei, Zou, Jie, Kratz, Karl, Deng, Zijun, Lendlein, Andreas, Ma, Nan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10316329/
https://www.ncbi.nlm.nih.gov/pubmed/37310722
http://dx.doi.org/10.1021/acsami.3c01481