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pH-dependent structural characteristics of lonidamine: (1)H and (13)C NMR study

Lonidamine (LND) is an anti-cancer drug with great potential as a metabolic modulator of chemotherapy, radiotherapy, hyperthermia, and photodynamic therapy in cancer treatment. LND affects several important aspects of cancer cell metabolism: it inhibits Complex I and II of the electron transport cha...

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Detalles Bibliográficos
Autores principales: Gupta, Pradeep Kumar, Orlovskiy, Stepan, Roman, Jeffrey, Pickup, Stephen, Nelson, David S., Glickson, Jerry D., Nath, Kavindra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10316351/
https://www.ncbi.nlm.nih.gov/pubmed/37404315
http://dx.doi.org/10.1039/d3ra01615c