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Action of econazole on Ca(2+) levels and cytotoxicity in OC2 human oral cancer cells

BACKGROUND/PURPOSE: Econazole is an antifungal drug. Antifungal activity of econazole against non-dermatophyte molds was reported. Econazole inhibited Ca(2+) channels and stimulated cytotoxicity in lymphoma and leukemia cells. Ca(2+) cations are crucial second envoy that triggers various processes....

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Detalles Bibliográficos
Autores principales: Wang, Jue-Long, Jan, Chung-Ren, Chen, Min-Huey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Association for Dental Sciences of the Republic of China 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10316490/
https://www.ncbi.nlm.nih.gov/pubmed/37404653
http://dx.doi.org/10.1016/j.jds.2023.02.013