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BRCA1/2 potential founder variants in the Jordanian population: an opportunity for a customized screening panel

A founder variant is a genetic alteration, that is inherited from a common ancestor together with a surrounding chromosomal segment, and is observed at a high frequency in a defined population. This founder effect occurs as a consequence of long-standing inbreeding of isolated populations. For high-...

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Detalles Bibliográficos
Autores principales: Ahmad, Olfat, Sutter, Christian, Hirsch, Steffen, Pfister, Stefan M., Schaaf, Christian P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10316545/
https://www.ncbi.nlm.nih.gov/pubmed/37400873
http://dx.doi.org/10.1186/s13053-023-00256-2