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Robustness of single-cell RNA-seq for identifying differentially expressed genes

BACKGROUND: A common feature of single-cell RNA-seq (scRNA-seq) data is that the number of cells in a cell cluster may vary widely, ranging from a few dozen to several thousand. It is not clear whether scRNA-seq data from a small number of cells allow robust identification of differentially expresse...

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Detalles Bibliográficos
Autores principales: Liu, Yong, Huang, Jing, Pandey, Rajan, Liu, Pengyuan, Therani, Bhavika, Qiu, Qiongzi, Rao, Sridhar, Geurts, Aron M., Cowley, Allen W., Greene, Andrew S., Liang, Mingyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10316566/
https://www.ncbi.nlm.nih.gov/pubmed/37394518
http://dx.doi.org/10.1186/s12864-023-09487-y