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Exosome-derived circKIF20B suppresses gefitinib resistance and cell proliferation in non-small cell lung cancer

BACKGROUND: The gefitinib resistance mechanism in non-small cell lung cancer (NSCLC) remains unclear, albeit exosomal circular RNA (circRNA) is known to possibly play a vital role in it. METHODS: We employed high-throughput sequencing techniques to detect the expressions of exosomal circRNA both in...

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Detalles Bibliográficos
Autores principales: Wei, Si-Liang, Ye, Jing-Jing, Sun, Li, Hu, Lei, Wei, Yuan-Yuan, Zhang, Da-Wei, Xu, Meng-Meng, Fei, Guang-He
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10316567/
https://www.ncbi.nlm.nih.gov/pubmed/37394466
http://dx.doi.org/10.1186/s12935-023-02974-y