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TAOK3 limits age-associated inflammation by negatively modulating macrophage differentiation and their production of TNFα

BACKGROUND: Human aging is characterized by a state of chronic inflammation, termed inflammaging, for which the causes are incompletely understood. It is known, however, that macrophages play a driving role in establishing inflammaging by promoting pro-inflammatory rather than anti-inflammatory resp...

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Detalles Bibliográficos
Autores principales: Poirier, Alexandre, Wu, Chenyue, Hincapie, Ana Maria, Martinez-Cordova, Zuzet, Abidin, Belma Melda, Tremblay, Michel L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10316641/
https://www.ncbi.nlm.nih.gov/pubmed/37400834
http://dx.doi.org/10.1186/s12979-023-00350-y