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Deep neural networks with knockoff features identify nonlinear causal relations and estimate effect sizes in complex biological systems
BACKGROUND: Learning the causal structure helps identify risk factors, disease mechanisms, and candidate therapeutics for complex diseases. However, although complex biological systems are characterized by nonlinear associations, existing bioinformatic methods of causal inference cannot identify the...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10316696/ https://www.ncbi.nlm.nih.gov/pubmed/37395630 http://dx.doi.org/10.1093/gigascience/giad044 |