Impaired ribosome-associated quality control of C9orf72 arginine-rich dipeptide-repeat proteins

Protein quality control pathways have evolved to ensure the fidelity of protein synthesis and efficiently clear potentially toxic protein species. Defects in ribosome-associated quality control and its associated factors have been implicated in the accumulation of aberrant proteins and neurodegenera...

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Detalles Bibliográficos
Autores principales: Viera Ortiz, Ashley P, Cajka, Gregory, Olatunji, Olamide A, Mikytuck, Bailey, Shalem, Ophir, Lee, Edward B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10316761/
https://www.ncbi.nlm.nih.gov/pubmed/36516294
http://dx.doi.org/10.1093/brain/awac479

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10316761/
https://www.ncbi.nlm.nih.gov/pubmed/36516294
http://dx.doi.org/10.1093/brain/awac479

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