A novel quantitative trait locus implicates Msh3 in the propensity for genome-wide short tandem repeat expansions in mice

Short tandem repeats (STRs) are a class of rapidly mutating genetic elements typically characterized by repeated units of 1–6 bp. We leveraged whole-genome sequencing data for 152 recombinant inbred (RI) strains from the BXD family of mice to map loci that modulate genome-wide patterns of new mutati...

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Detalles Bibliográficos
Autores principales: Maksimov, Mikhail O., Wu, Cynthia, Ashbrook, David G., Villani, Flavia, Colonna, Vincenza, Mousavi, Nima, Ma, Nichole, Lu, Lu, Pritchard, Jonathan K., Goren, Alon, Williams, Robert W., Palmer, Abraham A., Gymrek, Melissa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10317118/
https://www.ncbi.nlm.nih.gov/pubmed/37127331
http://dx.doi.org/10.1101/gr.277576.122

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10317118/
https://www.ncbi.nlm.nih.gov/pubmed/37127331
http://dx.doi.org/10.1101/gr.277576.122

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