Cargando…
Experimental systems for the analysis of mutational signatures: no ‘one-size-fits-all' solution
Cells constantly accumulate mutations, which are caused by replication errors, as well as through the action of endogenous and exogenous DNA-damaging agents. Mutational patterns reflect the status of DNA repair machinery and the history of genotoxin exposure of a given cellular clone. Computationall...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Portland Press Ltd.
2023
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10317150/ https://www.ncbi.nlm.nih.gov/pubmed/37283472 http://dx.doi.org/10.1042/BST20221482 |