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Chemical labeling and proteomics for characterization of unannotated small and alternative open reading frame-encoded polypeptides

Thousands of unannotated small and alternative open reading frames (smORFs and alt-ORFs, respectively) have recently been revealed in mammalian genomes. While hundreds of mammalian smORF- and alt-ORF-encoded proteins (SEPs and alt-proteins, respectively) affect cell proliferation, the overwhelming m...

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Detalles Bibliográficos
Autores principales: Chen, Yanran, Cao, Xiongwen, Loh, Ken H., Slavoff, Sarah A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10317152/
https://www.ncbi.nlm.nih.gov/pubmed/37171061
http://dx.doi.org/10.1042/BST20221074