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The molecular mechanisms of human separase regulation

Sister chromatid segregation is the final irreversible step of mitosis. It is initiated by a complex regulatory system that ultimately triggers the timely activation of a conserved cysteine protease named separase. Separase cleaves the cohesin protein ring that links the sister chromatids and thus f...

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Detalles Bibliográficos
Autores principales: Yu, Jun, Morgan, David O., Boland, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10317155/
https://www.ncbi.nlm.nih.gov/pubmed/37140261
http://dx.doi.org/10.1042/BST20221400