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Small molecule and peptide inhibitors of βTrCP and the βTrCP–NRF2 protein–protein interaction
The E3 ligase beta-transducin repeat-containing protein (βTrCP) is an essential component of the ubiquitin–proteasome system that is responsible for the maintenance of cellular protein levels in human cells. Key target substrates for degradation include inhibitor of nuclear factor kappa B, programme...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10317156/ https://www.ncbi.nlm.nih.gov/pubmed/37293994 http://dx.doi.org/10.1042/BST20220352 |