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Small molecule and peptide inhibitors of βTrCP and the βTrCP–NRF2 protein–protein interaction

The E3 ligase beta-transducin repeat-containing protein (βTrCP) is an essential component of the ubiquitin–proteasome system that is responsible for the maintenance of cellular protein levels in human cells. Key target substrates for degradation include inhibitor of nuclear factor kappa B, programme...

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Detalles Bibliográficos
Autores principales: Jaffry, Uzma, Wells, Geoff
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10317156/
https://www.ncbi.nlm.nih.gov/pubmed/37293994
http://dx.doi.org/10.1042/BST20220352