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The function and regulation of ADP-ribosylation in the DNA damage response

ADP-ribosylation is a post-translational modification involved in DNA damage response (DDR). In higher organisms it is synthesised by PARP 1–3, DNA strand break sensors. Recent advances have identified serine residues as the most common targets for ADP-ribosylation during DDR. To ADP-ribosylate seri...

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Detalles Bibliográficos
Autores principales: Duma, Lena, Ahel, Ivan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10317172/
https://www.ncbi.nlm.nih.gov/pubmed/37171085
http://dx.doi.org/10.1042/BST20220749