Cargando…

Dysregulated metabolism of the late herpes simplex virus 1 transcriptome through the vhs-VP22 axis uncouples virus cytopathic effect and virus production

Herpes simplex virus 1 (HSV1) expresses its genes in a classical cascade culminating in the production of large amounts of structural proteins to facilitate virus assembly. HSV1 lacking the virus protein VP22 (Δ22) exhibits late translational shutoff, a phenotype that has been attributed to the unre...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pheasant, Kathleen, Perry, Dana, Wise, Emma L., Cheng, Vivian, Elliott, Gillian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10317221/ https://www.ncbi.nlm.nih.gov/pubmed/37343008 http://dx.doi.org/10.1371/journal.ppat.1010966

Ejemplares similares

Multiple Posttranscriptional Strategies To Regulate the Herpes Simplex Virus 1 vhs Endoribonuclease
por: Elliott, Gillian, et al.
Publicado: (2018)

Herpes Simplex Virus 1 Expressing GFP-Tagged Virion Host Shutoff (vhs) Protein Uncouples the Activities of RNA Degradation and Differential Nuclear Retention of the Virus Transcriptome
por: Wise, Emma L., et al.
Publicado: (2022)

Nuclear-cytoplasmic compartmentalization of the herpes simplex virus 1 infected cell transcriptome is co-ordinated by the viral endoribonuclease vhs and cofactors to facilitate the translation of late proteins
por: Pheasant, Kathleen, et al.
Publicado: (2018)

The Study of the Intercellular Trafficking of the Fusion Proteins of Herpes Simplex Virus Protein VP22
por: Xue, Xiaodong, et al.
Publicado: (2014)

VP22 herpes simplex virus protein can transduce proteins into stem cells
por: Gabanyi, I., et al.
Publicado: (2013)

Non-cytopathic herpes simplex virus type-1 isolated from acyclovir-treated patients with recurrent infections
por: Roy, Subrata, et al.
Publicado: (2022)

VHS, US3 and UL13 viral tegument proteins are required for Herpes Simplex Virus-Induced modification of protein kinase R
por: Pennisi, Rosamaria, et al.
Publicado: (2020)

The herpes simplex virus host shutoff (vhs) RNase limits accumulation of double stranded RNA in infected cells: Evidence for accelerated decay of duplex RNA
por: Dauber, Bianca, et al.
Publicado: (2019)

Author Correction: VHS, US3 and UL13 viral tegument proteins are required for Herpes Simplex Virus-Induced modification of protein kinase R
por: Pennisi, Rosamaria, et al.
Publicado: (2021)

Nuclear export of VP19C is not essential for replication of herpes simplex virus type 1
por: Li, You, et al.
Publicado: (2014)

Herpes Simplex and Pseudorabies Viruses
por: Hierholzer, Walter J.
Publicado: (1970)

The interaction of Herpes Simplex Virus with murine lymphocytes. I. Mitogenic properties of herpes simplex virus
Publicado: (1977)

LYSOSOMAL ENZYMES IN CELLS INFECTED WITH CYTOPATHIC AND NON-CYTOPATHIC VIRUSES
por: Mallucci, L., et al.
Publicado: (1965)

CD8+ T Lymphocyte Epitopes From The Herpes Simplex Virus Type 2 ICP27, VP22 and VP13/14 Proteins To Facilitate Vaccine Design And Characterization
por: Platt, Rebecca J., et al.
Publicado: (2013)

Outbreak of viral haemorrhagic septicaemia (VHS) in lumpfish (Cyclopterus lumpus) in Iceland caused by VHS virus genotype IV
por: Guðmundsdóttir, Sigríður, et al.
Publicado: (2018)

VP22 core domain from Herpes simplex virus 1 reveals a surprising structural conservation in both the Alpha- and Gammaherpesvirinae subfamilies
por: Hew, Kelly, et al.
Publicado: (2015)

The Virion Host Shut-Off (vhs) Protein Blocks a TLR-Independent Pathway of Herpes Simplex Virus Type 1 Recognition in Human and Mouse Dendritic Cells
por: Cotter, Christopher R., et al.
Publicado: (2010)

Herpes Simplex Virus Infection in Pregnancy
por: Straface, Gianluca, et al.
Publicado: (2012)

Photodynamic Inactivation of Herpes Simplex Viruses
por: Monjo, Andrea L.-A., et al.
Publicado: (2018)

Oncolytic herpes simplex virus and immunotherapy
por: Ma, Wenqing, et al.
Publicado: (2018)

Palate herpes simplex virus infection
por: Mosaico, Giovanna, et al.
Publicado: (2020)

Developments in Vaccination for Herpes Simplex Virus
por: Krishnan, Rohini, et al.
Publicado: (2021)

Pathogenesis and virulence of herpes simplex virus
por: Zhu, Shuyong, et al.
Publicado: (2021)

DNA Binding and Condensation Properties of the Herpes Simplex Virus Type 1 Triplex Protein VP19C
por: Bera, Alakesh, et al.
Publicado: (2014)

Degradation of Herpes Simplex Virus-1 Viral miRNA H11 by Vaccinia Virus Protein VP55 Attenuates Viral Replication
por: Zou, Weixuan, et al.
Publicado: (2020)

Herpes Simplex Virus Type 2 Is More Difficult to Neutralize by Antibodies Than Herpes Simplex Virus Type 1
por: Silke Heilingloh, Christiane, et al.
Publicado: (2020)

The First Identified Nucleocytoplasmic Shuttling Herpesviral Capsid Protein: Herpes Simplex Virus Type 1 VP19C
por: Zhao, Lei, et al.
Publicado: (2012)

Herpes simplex and herpes zoster viruses in COVID-19 patients
por: Katz, Joseph, et al.
Publicado: (2021)

THE INACTIVATION OF HERPES SIMPLEX VIRUS BY PHOSPHATASE ENZYMES
por: Amos, Harold
Publicado: (1953)

An Unusual Presentation of Herpes Simplex Virus Encephalitis
por: Boyapati, Ray, et al.
Publicado: (2012)

Herpes Simplex Virus Encephalitis in Hamadan, Iran
por: Ghannad, Masoud Sabouri, et al.
Publicado: (2013)

The molecular basis of herpes simplex virus latency
por: Nicoll, Michael P, et al.
Publicado: (2012)

Disseminated Herpes Simplex Virus with Fulminant Hepatitis
por: Rimawi, Bassam H., et al.
Publicado: (2015)

Retargeting Strategies for Oncolytic Herpes Simplex Viruses
por: Campadelli-Fiume, Gabriella, et al.
Publicado: (2016)

Immunological control of herpes simplex virus infections
por: Egan, Kevin P., et al.
Publicado: (2013)

Dynamic Proteomics of Herpes Simplex Virus Infection
por: Drayman, Nir, et al.
Publicado: (2017)

Structure of the herpes simplex virus portal-vertex
por: McElwee, Marion, et al.
Publicado: (2018)

Adoption of Innovation in Herpes Simplex Virus Keratitis
por: Chodosh, James, et al.
Publicado: (2020)

Clinical Management of Herpes Simplex Virus Keratitis
por: Labib, Bisant A., et al.
Publicado: (2022)

Herpes Simplex Virus-Associated Aplastic Anemia
por: Hinojosa, Oscar A, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_btko4h43q48l9ah0qqjp4k479b