Regulatory logic of endogenous RNAi in silencing de novo genomic conflicts

Although the biological utilities of endogenous RNAi (endo-RNAi) have been largely elusive, recent studies reveal its critical role in the non-model fruitfly Drosophila simulans to suppress selfish genes, whose unchecked activities can severely impair spermatogenesis. In particular, hairpin RNA (hpR...

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Detalles Bibliográficos
Autores principales: Vedanayagam, Jeffrey, Lin, Ching-Jung, Papareddy, Ranjith, Nodine, Michael, Flynt, Alex S., Wen, Jiayu, Lai, Eric C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10317233/
https://www.ncbi.nlm.nih.gov/pubmed/37343034
http://dx.doi.org/10.1371/journal.pgen.1010787

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10317233/
https://www.ncbi.nlm.nih.gov/pubmed/37343034
http://dx.doi.org/10.1371/journal.pgen.1010787

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