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Regulatory logic of endogenous RNAi in silencing de novo genomic conflicts
Although the biological utilities of endogenous RNAi (endo-RNAi) have been largely elusive, recent studies reveal its critical role in the non-model fruitfly Drosophila simulans to suppress selfish genes, whose unchecked activities can severely impair spermatogenesis. In particular, hairpin RNA (hpR...
Autores principales: | Vedanayagam, Jeffrey, Lin, Ching-Jung, Papareddy, Ranjith, Nodine, Michael, Flynt, Alex S., Wen, Jiayu, Lai, Eric C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10317233/ https://www.ncbi.nlm.nih.gov/pubmed/37343034 http://dx.doi.org/10.1371/journal.pgen.1010787 |
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