Transgenic murine models for the study of drug hypersensitivity reactions linked to HLA-I molecules

Immune-mediated drug hypersensitivity reactions (DHRs) can be life-threatening and an impediment to drug development. Mechanism of disease studies are difficult to perform in humans. Here we review human leukocyte antigens class I (HLA-I) transgenic murine models and highlight how these systems have...

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Detalles Bibliográficos
Autores principales: Puig, Montserrat, Norcross, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
DRUG ALLERGY: Edited by Luciana Tanno and Dean Naisbitt
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10317295/
https://www.ncbi.nlm.nih.gov/pubmed/37284777
http://dx.doi.org/10.1097/ACI.0000000000000913

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10317295/
https://www.ncbi.nlm.nih.gov/pubmed/37284777
http://dx.doi.org/10.1097/ACI.0000000000000913

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