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Perillyl alcohol modulates activation, permeability and integrity of human brain endothelial cells induced by Plasmodium falciparum

BACKGROUND: Cerebral malaria (CM) is a severe immunovasculopathy caused for Plasmodium falciparum infection, which is characterised by the sequestration of parasitised red blood cells (pRBCs) in brain microvessels. Previous studies have shown that some terpenes, such as perillyl alcohol (POH), exhib...

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Detalles Bibliográficos
Autores principales: Marin, Adriana A, Juillard, Annette, Katzin, Alejandro M, Carvalho, Leonardo JM, Grau, Georges ER
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Instituto Oswaldo Cruz, Ministério da Saúde 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10317308/
https://www.ncbi.nlm.nih.gov/pubmed/37403869
http://dx.doi.org/10.1590/0074-02760230033