Interplay between VSD, pore, and membrane lipids in electromechanical coupling in HCN channels

Hyperpolarized-activated and cyclic nucleotide-gated (HCN) channels are the only members of the voltage-gated ion channel superfamily in mammals that open upon hyperpolarization, conferring them pacemaker properties that are instrumental for rhythmic firing of cardiac and neuronal cells. Activation...

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Detalles Bibliográficos
Autores principales: Elbahnsi, Ahmad, Cowgill, John, Burtscher, Verena, Wedemann, Linda, Zeckey, Luise, Chanda, Baron, Delemotte, Lucie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Structural Biology and Molecular Biophysics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10317503/
https://www.ncbi.nlm.nih.gov/pubmed/37341381
http://dx.doi.org/10.7554/eLife.80303

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10317503/
https://www.ncbi.nlm.nih.gov/pubmed/37341381
http://dx.doi.org/10.7554/eLife.80303

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