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Genetic profiling of circulating cell‐free DNA from cerebrospinal fluid and paired plasma in ALK‐positive lung cancer with brain metastases

BACKGROUND: This study used next‐generation sequencing (NGS) to investigate the genetic profiles in cerebrospinal fluid (CSF), plasma, and tumor tissue to explore alternative detection methods for anaplastic lymphoma kinase (ALK) rearrangement status and potential resistance mechanisms to ALK inhibi...

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Detalles Bibliográficos
Autores principales: Shi, Liang, Guo, Lili, Tao, Hong, Meng, Qiyi, Tong, Li, Tang, Junfang, Li, Kun, Zhang, Shucai, Liu, Zhe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Australia, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10317598/
https://www.ncbi.nlm.nih.gov/pubmed/37287428
http://dx.doi.org/10.1111/1759-7714.14936