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Spatial single cell analysis of tumor microenvironment remodeling pattern in primary central nervous system lymphoma

To determine the overall tumor microenvironment (TME), characteristics, and transition mechanisms in primary central nervous system lymphoma (PCNSL), we performed spatial transcriptomics and matched the corresponding single-cell sequencing data of PCNSL patients. We found that tumor cells may achiev...

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Detalles Bibliográficos
Autores principales: Xia, Yuan, Sun, Tao, Li, Guosheng, Li, Mingying, Wang, Dongmei, Su, Xiuhua, Ye, Jingjing, Ji, Chunyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10317840/
https://www.ncbi.nlm.nih.gov/pubmed/37120690
http://dx.doi.org/10.1038/s41375-023-01908-x