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Glucose-stimulated insulin secretion depends on FFA1 and Gq in neonatal mouse islets

AIMS/HYPOTHESIS: After birth, the neonatal islets gradually acquire glucose-responsive insulin secretion, a process that is subjected to maternal imprinting. Although NEFA are major components of breastmilk and insulin secretagogues, their role for functional maturation of neonatal beta cells is sti...

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Detalles Bibliográficos
Autores principales: Lorza-Gil, Estela, Kaiser, Gabriele, Carlein, Christopher, Hoffmann, Markus D. A., König, Gabriele M., Haug, Sieglinde, Prates Roma, Leticia, Rexen Ulven, Elisabeth, Ulven, Trond, Kostenis, Evi, Birkenfeld, Andreas L., Häring, Hans-Ulrich, Ullrich, Susanne, Gerst, Felicia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10317898/
https://www.ncbi.nlm.nih.gov/pubmed/37217659
http://dx.doi.org/10.1007/s00125-023-05932-5