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Development and characterization of an intra-articular fracture mediated model of post-traumatic osteoarthritis

PURPOSE: This study aimed to develop and characterize a closed intra-articular fracture (IAF) mediated post-traumatic osteoarthritis (PTOA) model in rats to serve as a testbed for putative disease modifying interventions. METHODS: Male rats were subject to a 0 Joule (J), 1 J, 3 J, or 5 J blunt-force...

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Detalles Bibliográficos
Autores principales: Valerio, Michael S., Pace, William A., Dolan, Connor P., Edwards, Jorge B., Janakiram, Naveena B., Potter, Benjamin K., Dearth, Christopher L., Goldman, Stephen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10317931/
https://www.ncbi.nlm.nih.gov/pubmed/37400744
http://dx.doi.org/10.1186/s40634-023-00625-9