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Characterization of a spontaneous mouse model of mild, accelerated aging via ECM degradation in emphysematous lungs

Emphysema limits airflow and causes irreversible progression of chronic obstructive pulmonary disease (COPD). Strain differences must be considered when selecting mouse models of COPD, owing to disease complexity. We previously reported that a novel C57BL/6JJcl substrain, the Mayumi-Emphysema (ME) m...

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Detalles Bibliográficos
Autores principales: Tanino, Ryosuke, Tsubata, Yukari, Hotta, Takamasa, Okimoto, Tamio, Amano, Yoshihiro, Takechi, Mayumi, Tanaka, Tetsuya, Akita, Tomomi, Nagase, Mamiko, Yamashita, Chikamasa, Wada, Koichiro, Isobe, Takeshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10317985/
https://www.ncbi.nlm.nih.gov/pubmed/37400563
http://dx.doi.org/10.1038/s41598-023-37638-4