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Assessing biological network dynamics: comparing numerical simulations with analytical decomposition of parameter space

Mathematical modeling of the emergent dynamics of gene regulatory networks (GRN) faces a double challenge of (a) dependence of model dynamics on parameters, and (b) lack of reliable experimentally determined parameters. In this paper we compare two complementary approaches for describing GRN dynamic...

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Detalles Bibliográficos
Autores principales: Hari, Kishore, Duncan, William, Ibrahim, Mohammed Adil, Jolly, Mohit Kumar, Cummins, Breschine, Gedeon, Tomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10318016/
https://www.ncbi.nlm.nih.gov/pubmed/37400474
http://dx.doi.org/10.1038/s41540-023-00289-2